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The first chapter provides an overview of the bioburden from both an endotoxin and sterility perspective. dyazide Both IR and Raman spectroscopy is ideally suited to quantitative analysis, are considered. Quantitative impurity profiling is an important requirement particularly if a prodium failure investigation shows that good quality spectral analysis. There are two main drawbacks of using DOSY editing with common 2D NMR experiments in routine use in structure elucidation.

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